Food Standards Agency - Recent allergy alerts

Friday, 7 January 2011

The role of shellfish proteases in allergic diseases and inflammation

"This review outlines the different roles of proteases in allergic and inflammatory reactions. Preliminary data from our group demonstrate for the first time the presence of four types of proteases in rock lobster and two shrimp species. Trypsin-like activity seems to be the major enzyme action in all three shellfish species, with the highest proteolytic activity occurring under physiological conditions similar to those of the lung environment. This study is the foundation for further investigations into the role of proteases in allergic and inflammatory reactions towards exposure to shellfish allergens in the occupational and domestic environment."


S Sun, A.L Lopata
The role of shellfish proteases in allergic diseases and inflammation.
Current Allergy and Clinical Immunology 2010;23(4):174-179

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